Arsameia on the Nymphaios is an ancient city located in Old Kâhta in the Turkish province of Adıyaman. The site is near Kâhtaçay, known in ancient times as Nymphaios. Arsameia was a royal seat of the kingdom of Commagene. It is best known for the Hierothesion of King Mithridates I Kallinikos, built for him by his son and heir Antiochos I.

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